Introduction: The WHO has developed medication use indicators, including prescription indicators with an aim to evaluate the services provided to the population in regard to medications.With the help of these indicators, there will be anti-age hals constant watch on drug prescribing pattern in health care to avoid irrational prescribing.Objectives:
Intrinsic dynamics study identifies two amino acids of TIMP-1 critical for its LRP-1-mediated endocytosis in neurons
Abstract The tissue inhibitor of metalloproteinases-1 (TIMP-1) exerts inhibitory activity against matrix metalloproteinases and cytokine-like effects.We previously showed that TIMP-1 reduces neurite outgrowth in mouse cortical neurons and that this cytokine-like effect depends on TIMP-1 endocytosis mediated by the low-density Freeride / Crossover l
Effectiveness and mechanical characteristics of a pile-beam composite structure in blocking debris flows
The pile-beam Spotlight Modules composite structure in high-elevation debris flow areas is selected as the research object.Based on characterizing the pile-beam composite structure, the particle-flow simulation analysis program and the explicit dynamic analysis program were used to study comparatively the blocking effects of single-row piles and tw
Testicular torsion and weather conditions: analysis of 21,289 cases in Brazil
PURPOSE: The hypothesis of association between testicular torsion and hyperactive cremasteric reflex, worsened by cold weather, has not been proved.Thirteen studies in the literature evaluated this issue, with inconclusive results.The aim of the present study was to evaluate the seasonality of testicular torsion in a large subset of patients surgic